All shops selling non-essential goods will be closed immediately as the government imposes tougher controls to try and fight the coronavirus.
The shutdown will include clothing and electronic shops and other premises such as chocolate and book chains.
However, shops which sell essential items, such as supermarkets and pharmacies, will remain open.
Prime Minister Boris Johnson said the measures would cause disruption but save lives.
A host of High Street retailers and food chains, such as Ikea, John Lewis and Next, have already shut, leaving tens of thousands of people temporarily without work.